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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPNPEP3 All Species: 18.18
Human Site: T53 Identified Species: 40
UniProt: Q9NQH7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQH7 NP_071381.1 507 57034 T53 L G Q P S P F T H P H L L R P
Chimpanzee Pan troglodytes XP_515152 507 56971 T53 L G Q P S P F T H P H L L R P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538358 507 57092 T53 L G Q P S P F T H P H L L R P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508206 540 60603 T86 L G Q P S P F T H P H L L R P
Chicken Gallus gallus XP_416240 502 56268 K53 F T H P H L L K P G E V T P G
Frog Xenopus laevis NP_001086945 502 56377 P53 T H P Q C L K P G E V T P G L
Zebra Danio Brachydanio rerio NP_996962 510 56616 T57 L G Q P S P Y T H P H L I R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608376 545 60861 L78 T S V S H P H L I Q P D E L V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793902 510 57147 Y54 Y I G Q P T S Y T H Q H L L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172401 493 54963 I54 E V T P G I R I E E Y I G R R
Baker's Yeast Sacchar. cerevisiae P40051 511 57971 L55 L H E T R P F L I K S G E L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 92.9 N.A. N.A. N.A. N.A. 77.9 78.1 67 57.2 N.A. 34.3 N.A. N.A. 50.7
Protein Similarity: 100 99.6 N.A. 96.4 N.A. N.A. N.A. N.A. 86.4 88.9 82 73.3 N.A. 55.5 N.A. N.A. 68
P-Site Identity: 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 6.6 0 80 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 13.3 0 93.3 N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 37.6 34 N.A.
Protein Similarity: N.A. N.A. N.A. 57.7 54.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 10 0 0 0 0 0 10 19 10 0 19 0 0 % E
% Phe: 10 0 0 0 0 0 46 0 0 0 0 0 0 0 0 % F
% Gly: 0 46 10 0 10 0 0 0 10 10 0 10 10 10 10 % G
% His: 0 19 10 0 19 0 10 0 46 10 46 10 0 0 10 % H
% Ile: 0 10 0 0 0 10 0 10 19 0 0 10 10 0 0 % I
% Lys: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % K
% Leu: 55 0 0 0 0 19 10 19 0 0 0 46 46 28 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 64 10 64 0 10 10 46 10 0 10 10 37 % P
% Gln: 0 0 46 19 0 0 0 0 0 10 10 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 10 0 0 0 0 0 0 55 19 % R
% Ser: 0 10 0 10 46 0 10 0 0 0 10 0 0 0 0 % S
% Thr: 19 10 10 10 0 10 0 46 10 0 0 10 10 0 10 % T
% Val: 0 10 10 0 0 0 0 0 0 0 10 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 10 10 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _